He worked for seven years on the TV programme The South Bank Show, before becoming Culture Editor of Channel 4 News in 2010. He left Channel 4 in 2013, in order to write fiction.
Matthew Cain was listed in the "Journalists" section of the Pink List 2012. The citation said:
- "Spent 10 years making documentaries before stepping in front of the camera; now reports on arts news and fronts shows such as What Makes a Masterpiece?. First novel out in 2014."
- http://www.pinknews.co.uk/2013/04/24/culture-editor-matthew-cain-to-leave-channel-4-news/ Scott Roberts, "Culture Editor Matthew Cain to leave Channel 4 News" Pink News 24 April 2013