She was MP for Birmingham Edgbaston from 1966 to 1997. She was made a Dame in 1985, and a life peer in 1997.
She was largely responsible for introducing the Section 28 amendment to the Local Government Act 1988, which barred local authorities from promoting homosexuality. She was also an opponent of abortion, and supported successive attempts to reduce the period during which the operation could be legally performed.
In June 2013, she opposed same-sex marriage, arguing that Parliament cannot change the fact that "marriage is not about just love. It is about a man and a woman, themselves created to produce children, producing children. A man can no more bear a child, than a woman can produce sperm, and no law on earth can change that. This is not a homophobic view. It may be sad, it may be unequal, but it's true."
- http://www.theguardian.com/world/2015/jun/07/section-28-anti-gay-law-was-not-devised-in-department-of-education Nicholas Billingham, "Section 28 anti-gay law was not devised in the Department of Education". The Guardian (Letters) 7 June 2015}
- http://www.pinknews.co.uk/2013/06/03/baroness-knight-parliament-cant-help-blind-people-see-so-cant-help-artistic-gays-get-married Joseph Patrick McCormick, "Baroness Knight: Parliament can't help blind people see, so can't help 'artistic' gays get married'". Pink News, 3 June 2013