He was educated at Eton and Pembroke College, Oxford. He was a friend of Evelyn Waugh at Oxford (A L Rowse believed the two to be lovers), where both were members of the Hypocrites' Club. After leaving Oxford he worked in a bank in Paris before working in the City, but became dependent on alcohol.
In 1936 Lygon was on a motoring tour with his friend, the artist Henry Winch, son of Lady Newborough. He was standing in the road to ask the way and fell backwards, hitting his head on a stone. He died later due to a fractured skull, having spent four days in a hospital in Rothenburg. His body was later returned to England.
- Pronounced liggŏn, IPA ['lɪgən] – BBC Pronouncing Dictionary of British Names, Oxford University Press, 1971
- Paula Byrne, Mad World, Evelyn Waugh and the secrets of Brideshead, HarperPress, 2009, ISBN 978-0-00-790371-9